Question 1

What is the primary mechanism of action of ACE inhibitors such as lisinopril?

Accepted Answer

ACE inhibitors block the conversion of angiotensin I to angiotensin II, reducing vasoconstriction and aldosterone secretion, thereby lowering blood pressure.

Question 2

Which drug classification does warfarin (Coumadin) belong to, and what clotting factors does it inhibit?

Accepted Answer

Warfarin is an anticoagulant that inhibits vitamin K-dependent clotting factors II, VII, IX, and X.

Question 3

What class of drugs are SSRIs, and what is their primary mechanism of action?

Accepted Answer

SSRIs (Selective Serotonin Reuptake Inhibitors) are antidepressants that block the reuptake of serotonin into the presynaptic neuron, increasing serotonin availability in the synapse.

Question 4

What is the mechanism of action of loop diuretics such as furosemide (Lasix)?

Accepted Answer

Loop diuretics inhibit the Na-K-2Cl cotransporter in the thick ascending loop of Henle, preventing sodium and water reabsorption and producing potent diuresis.

Question 5

Beta-1 selective adrenergic blockers primarily affect which organ, and what is the clinical result?

Accepted Answer

Beta-1 selective blockers (e.g., metoprolol, atenolol) primarily affect the heart, reducing heart rate, contractility, and blood pressure.

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